Illinois General Assembly: Multiple Myeloma Stage 1

Friday, August 20, 2021

Multiple Myeloma Stage 1

A variety of factors ultimately influence a patients decision to receive treatment of cancer. The ISS divides myeloma into 3 stages.

Multiple Myeloma Staging System Page 1 Line 17qq Com

The classification is based on the data collected from people with multiple myeloma across the globe.

Multiple myeloma stage 1. This earliest phase is called smoldering multiple myeloma. Stage of Disease. For multiple myeloma there are 3 stages.

Only a small number of the cancer cells can be found and they are in a localized area. Stage I multiple myeloma occurs when there is a relatively small amount of cancer in the body. Multiple myeloma is a cancer of the plasma cells.

The SEER database however does not group cancers by the Revised International Staging System stage 1 stage 2 stage 3. The levels of beta-2 microglobulin may be slightly higher than normal and the levels of albumin a water soluble protein may have decreased. The first line of treatment is also called induction or frontline therapy.

Stage I The levels of serum β2-M greater than 35 mgL with serum albumin of 35 gdL or more. The purpose of receiving cancer treatment may be to improve symptoms through local control of the cancer increase a patients chance of cure or prolong a patients survival. Myeloma that doesnt present with active symptoms is called the smoldering stage It may be undetectable in the blood in this stage.

Instead it groups cancers into localized regional and distant stages. In killing myeloma cells therapy reduces the amount of monoclonal protein and halts further medical problems related to multiple myeloma. This means that there are myeloma cells.

The level of the protein called beta 2 microglobulin ß2-microglobulin or ß2-M is less than 35 milligrams per litre mgL. Your age- you are 52 while the average MM patient is 69. If the plasma cell tumor is not in a bone it may be removed with surgery.

Generally the higher the stage number the larger the amount of the myeloma in the body. Oncologists using the Durie-Salmon system look at X-rays and count bone lesions. Your early stage at diagnosis- you were SMM for two years before progressing to early stage MM.

Multiple myeloma cells in fact produce various factors grouped under the name OAF Osteoclast Activating Factor s that allow osteoclasts to accelerate the demolition of bone tissue by resorption. T ests indicate there are a relatively small number of myeloma cells. Potential prognostic factors were evaluated using a variety of statistical techniques.

If you are diagnosed and treated in stage 1 for example you have a better survival rate than you would if you were diagnosed with stage 2 or 3 multiple myeloma. Clinical and laboratory data were gathered on 10750 previously untreated symptomatic myeloma patients from 17 institutions including sites in North America Europe and Asia. The stages of multiple myeloma as defined by the International Staging System are.

IgG Kappa- low risk- no genetic abnormalities-. When you have it you wont have any symptoms but your test results will show. Treatment Options for Multiple Myeloma by Stage These are often treated with radiation therapy.

The classification is based on the levels of serum albumin and the levels of serum β2-M. Stage I stage 1 multiple myeloma. Talk to your doctor if you have questions about staging.

They also test blood and urine to measure levels of hemoglobin a protein that transports oxygen in the blood calcium a mineral released when. First introduced in the 1970s the Durie-Salmon staging system is still used by some doctors to stage multiple myeloma. The plasma cells are a type of white blood cell present in the bone marrow.

In multiple myeloma bone damage is secondary to the appearance of lytic type lesions and osteopenia related to the proliferation of myeloma plasma cells in the medullary cavity. Often the stages 1 to 3 are written as the Roman numerals I II and III. Your physical condition- youre in good physical condition.

The SEER database tracks 5-year relative survival rates for multiple myeloma in the United States based on how far the cancer has spread. Here we present you the international staging system. What Are First Line Treatments in Myeloma.

The survival rates of multiple myeloma are estimated based on epidemiologic data collected by the National Cancer Institutes SEER program. Myeloma that isnt causing active symptoms is called the smoldering stage or Durie-Salmon stage 1. In 2005 a new staging system was developed by the IMFs research division the International Myeloma Working Group IMWG.

The number of cancer cells is measured by the level of two specific proteins albumin and beta-2-microglobulin.

Iss Staging Of Multiple Myeloma Download Table